Hepatocyte-Specific Deletion of HIF2α Prevents NASH-Related Liver Carcinogenesis by Decreasing Cancer Cell Proliferation.

This was accompanied by a significant reduction in the mRNA levels of matrix metalloprotease 9 and α-SMA ( Figure 5 B and C ), and by a trend for decreased collagen Sirius Red staining ( Figure 5 D ), despite that differences did not reach statistical significance.

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