The number of osteoclasts just showed a trend of increase in the aged (18‐month‐old) mice compared with the 3‐month‐old adult mice, but osteoclast activity was markedly augmented with aging, as revealed by TRAP staining (Figure S8C,S8D , Supporting Information) and ELISA for the serum bone resorption marker C‐terminal telopeptides of type I collagen (CTX‐I; Figure S8E , Supporting Information).
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Neuronal Induction of Bone-Fat Imbalance through Osteocyte Neuropeptide Y.
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