Although the reductions in the proinflammatory cytokine/chemokine were not found significant, all monkeys that received the Fh15 treatment showed a trend of reduced concentrations in plasma of all proinflammatory cytokines and chemokines measured, while concurrently modulating the population of innate immune cells in the blood.
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Recombinant Fasciola hepatica Fatty Acid Binding Protein as a Novel Anti-Inflammatory Biotherapeutic Drug in an Acute Gram-Negative Nonhuman Primate Sepsis Model.
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