Ghrelin and Cannabinoid Functional Interactions Mediated by Ghrelin/CB₁ Receptor Heteromers That Are Upregulated in the Striatum From Offspring of Mice Under a High-Fat Diet.

Functionality was, however, found when cells were treated with ghrelin and there was no additive effect at concentration of 10 nM ACEA or higher; the lower concentration of ACEA (1 nM) showed a trend to increase the ghrelin-induced effect ( Figure 3A ).

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