Epigenetic Dysregulation of Trophoblastic Gene Expression in Gestational Trophoblastic Disease.

Biomedicines · 2021 · PMC8698431 · PMID 34944751

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moderately significantno p-value reported

The above-described changes in the expression of the DNA methylase machinery, including the non-significant upregulation of DNMT3B at the RNA level and moderately significant upregulation at the protein level in complete moles may be ‘sufficient’ only for limited pathological changes to the trophoblast compared to choriocarcinoma.

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