Combination of Immune Checkpoint Inhibitors and Liver-Specific Therapies in Liver-Metastatic Uveal Melanoma: Can We Thus Overcome Its High Resistance?

A categorization by surgical resection of liver metastases demonstrated a highly significant difference ( p = 0.005) in OS between those patients who underwent surgical resection (median OS 32.8 months; 95% CI, 21.42–44.18; n = 11) and those who did not (median OS 12.20 months; 95% CI; 5.58–18.82, n = 31) ( Figure 3 A).

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Accordingly, a trend towards a higher median OS in Cohort 1.1 could be seen, even though this difference did not reach statistical significance ( p = 0.074) ( Figure 3 B). 3.4.

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