Moreover, intracellular LGR6 also showed a trend of increased expression at the interphase between bronchioles and alveoli, where club (CC10 + ) and basal progenitors (p63 + and CK5 + ) expanded towards the alveolar region ( Supplementary Figure S3E–G ).
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Increased LGR6 Expression Sustains Long-Term Wnt Activation and Acquisition of Senescence in Epithelial Progenitors in Chronic Lung Diseases.
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