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Decreased Circulating Melatonin with Loss of Age-Related Biphasic Change in Patients with Oral Squamous Cell Carcinoma.

J Pers Med · 2021 · PMC8704174 · PMID 34945828

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Although the difference did not reach statistical significance, we did observe a trend of lower melatonin levels in healthy controls who chewed betel quid compared to those who did not ( Table 2 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.