Semi-Quantitative Multiplex Profiling of the Complement System Identifies Associations of Complement Proteins with Genetic Variants and Metabolites in Age-Related Macular Degeneration.

These associations did not reach statistical significance after FDR correction, but 173 suggestive associations with complement peptide levels with a p -value < 0.05 prior to FDR correction were identified ( Supplementary Table S19 ).

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The median FH level comparisons with CFH locus variants showed borderline significance between different genotypes and can be seen in Supplementary Figure S2A–C .

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