Treosulfan clearance of <7.97 L/h/m 2 was significantly associated with poor OS and EFS; where as high Treosulfan clearance (>7.97 L/h/m2) and low AUC (<1,828 mg.h/L) showed a trend toward better OS ( 151 ).
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Total Body Irradiation Forever? Optimising Chemotherapeutic Options for Irradiation-Free Conditioning for Paediatric Acute Lymphoblastic Leukaemia.
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