Comparison of Efficacy among Three Dermal Substitutes in the Management of Critical Lower-Limb Wounds: The Largest Biases-Reduced Single-Center Retrospective Cohort Study in Literature.

Eventually, the comparison exclusively between skin-grafted “acute” wounds showed that Pelnac ® has a lower percentage of graft take (63%) but a higher rate of wound healing at 30 days (86%); even if not statistically significant, these percentages mirrored the same observed for the undivided sample and clearly showed a trend in a stronger secondary healing stimulation by Pelnac ® .

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