In addition, IL-22 serum levels were on average slightly higher in K8 flox/flox ; Villin-Cre compared to K8 flox/flox , but did not reach statistical significance ( P = 0.099), while IL-25 was below the detection limit (3.8 pg/ml).
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Targeted deletion of keratin 8 in intestinal epithelial cells disrupts tissue integrity and predisposes to tumorigenesis in the colon.
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0.0990
0.0990