Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis.

In addition, the increased level of alanine transaminase, a common measure for liver injury, observed in the liver of HFD-fed wild-type mice was reduced by ∼30% in the absence of CPEB4, although the difference did not reach statistical significance ( Figure 6 C).

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