Complement activation induces excessive T cell cytotoxicity in severe COVID-19.

Cell · 2022 · PMC8712270 · PMID 35032429

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Furthermore, proportions of CD3 + CD16 + HLA-DR + T cells measured by multicolor flow cytometry ( Figure S4 B ) and activated FCGR3A expressing scRNA-seq clusters ( Figure S4 C) in samples from cohort 2 showed a trend to be higher in severe COVID-19 patients who deceased during follow up.

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