Barely Significant
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Global experience with PSMA-based alpha therapy in prostate cancer.

Eur J Nucl Med Mol Imaging · 2021 · PMC8712297 · PMID 34173838

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may be significantno p-value reported
The energy of the recoil effect may be significant enough to cause the breakage of the bond between the daughter radionuclide and the ligand.

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In the Indian series by Yadav and colleagues, PFS and OS were shorter in patients with a history of prior 177 Lu-PSMA therapy compared with patients without; the difference did not reach statistical significance, however, probably due to the small study population [ 77 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.