Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.

Proc Natl Acad Sci U S A · 2021 · PMC8713784 · PMID 34911760

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did not reach statistical significanceno p-value reported

Methylation differences between cases and controls in the second cohort trended in the same direction as the discovery cohort (i.e., hypomethylation) but did not reach statistical significance ( Fig. 2 A ).

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