Pharmacodynamic effects of direct AMP kinase activation in humans with insulin resistance and non-alcoholic fatty liver disease: A phase 1b study.

Cell Rep Med · 2021 · PMC8714938 · PMID 35028615

Europe PMC DOI

hedged sentence

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

showed a trendp = 0.074so close (0.05 < p ≤ 0.1)

The mean AUC (during the 10 h test period) showed a trend for DNL to decrease from baseline to week 4 by 17.45%∗h in PXL770 subjects ( Figure 3 B, p = 0.074) in the mITT analysis.

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