Yet, the reduction in BP with MAD compared to inactive controls (inactive/placebo oral appliance, conservative measures) did not reach statistical significance (mean change −1.55 mm Hg [95% CI −3.92 to 0.82], p = .20, and mean change −1.14 mm Hg [95% CI −2.87 to 0.59], p = .20 for systolic and diastolic BP, respectively. 7.2.
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Obstructive sleep apnea therapy for cardiovascular risk reduction-Time for a rethink?
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