Liraglutide Inhibits Osteoclastogenesis and Improves Bone Loss by Downregulating Trem2 in Female Type 1 Diabetic Mice: Findings From Transcriptomics.

type 1 diabetes bone loss bone density bone microarchitecture osteoclastogenesis Triggering receptor expressed on myeloid cells 2 liraglutide transcriptomics Effects of Liraglutide on Bone Mineral Density and Microarchitectures In the tibia, saline-treated T1D mice showed reduction in cortical volumetric bone mineral density (Ct.vBMD) and cortical thickness (Ct.Th) compared with NGT controls, while the difference in cortical thickness did not reach statistical significance ( Figures 2 , 3 and Supplementary Table 4 ).

also in 111,027 other papers