The ARC was not significantly activated, although a clear trend towards increased cFOS reactivity due to Fc-GLP-1 was present ( Figure 7 B).
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Peptide-YY<sub>3-36</sub>/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
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