Barely Significant
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Peptide-YY<sub>3-36</sub>/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.

Mol Metab · 2022 · PMC8717237 · PMID 34781035

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a clear trendno p-value reported
The ARC was not significantly activated, although a clear trend towards increased cFOS reactivity due to Fc-GLP-1 was present ( Figure 7 B).

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