Consistent with the lower STAT1 expression, the memory CD8 T cell subset showed lower STAT1 activation than naive CD8 T cells, and while an enhanced trend was observed in PLWH did not reach statistical significance ( Figure 1 C).
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IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT<sup>+</sup> HIVGag-specific T cells.
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