Furthermore, the depression descriptor variable in model M2 is highly significant (p-value: 1.39E-12), which further confirms that depression can be considered a relevant factor in the etiology of migraine.
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A replication study separates polymorphisms behind migraine with and without depression.
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The sentences
Our main effect analysis for migraine demonstrated only 6 nominally significant SNPs, and among them only one could be associated with a gene, the intron region of PRDM16 : rs2455107.