Reply: Biological Plausibility Behind the Benefits of Intravenous Metoprolol in Severe COVID-19.

J Am Coll Cardiol · 2022 · PMC8722669 · PMID 34991793

Europe PMC DOI

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a strong trendno p-value reported

Beyond an effect on the ratio of Pa o 2 to the fraction of inspired oxygen, we observed a strong trend toward a reduction in days on MV and of intensive care unit admission.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.