C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation.

Interestingly, FSK treatment showed a trend towards increased poly‐GP levels, when the poly‐GP levels of all lines were analysed together (Fig 7B ), which was significant in two of the three lines when the data were analysed individually (Appendix Fig S11D–F ).

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