Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs.

Front Immunol · 2021 · PMC8725049 · PMID 34992596

Europe PMC DOI

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While rhPRG4 treatment showed a trend towards a reduction in PL IL-1β at 24h in Prg4 GT/GT animals, this trend was not statistically significant ( p>0.05 ), due to a high degree of variability in calculated IL-1β concentrations in specimens from the same experimental group.

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