Loss of full-length pumilio 1 abrogates miRNA-221-induced gene p27 silencing-mediated cell proliferation in the heart.

Mol Ther Nucleic Acids · 2022 · PMC8728526 · PMID 35036057

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a strong trendno p-value reported

Although Ki67 staining indicated a significant increase of proliferating cells in the infarct compared with the remote myocardium, miR-221 treatment did not increase Ki67+ cells, and instead showed a strong trend toward reduced cell proliferation ( Figure 8 E).

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