3 ), the associations of three BCAA, alanine, and glycine with T2D risk were markedly stronger in the no-lag analysis, though highly significant at both times.
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Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study.
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Thirty-one 10-year metabolite changes showed a nominally significant T2D risk trend across quintile-based categories (P trend < 0.05) and were significant after multiple testing correction in the continuous analysis (FDR < 0.05, Wald test) ( Table 2 and Supplemental Tables 3 and 4 ).