Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease.

Front Cardiovasc Med · 2021 · PMC8739867 · PMID 35004919

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showed a trendno p-value reported

The ventricular/slow myosin heavy chain isoform ( Myh7 ), a gene associated with increased fibrosis and hypertrophic cardiomyopathy ( 36 ), showed a trend to increase in the BACHD ( Figure 4B ), with no significant changes in the BMYO in comparison to the WT.

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