Inflammasome activation in neutrophils of patients with severe COVID-19.

Blood Adv · 2022 · PMC8741335 · PMID 34991159

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highly significantno p-value reported

As others before us, 15 we observed a highly significant increase in plasma levels of NET biomarkers H3cit, DNA-myeloperoxidase complexes, and double-stranded DNA ( Figure 1C-E ).

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a strong trendno p-value reported

Considering the low sample number, we were not able to find a statistically significant correlation between speck and H3Cit + nuclei in neutrophils in tracheal aspirates, although a strong trend toward correlation was noted ( Figure 3E ).

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