Colorectal Cancer in North-Eastern Iran: a retrospective, comparative study of early-onset and late-onset cases based on data from the Iranian hereditary colorectal cancer registry.

Although family history of cancer overall did not align with any of the two age categories studied at a statistical significant level, the presence of a positive history of CRC in SDR together with early-onset CRC was highly significant and the combination with either FDR or SDR did not reach significance.

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With respect to anatomical tumour location (distal, rectal and proximal), the frequencies were 61, 28 and 11%, respectively, but the variation did not reach statistical significance.

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