Systemic macrophage depletion attenuates infarct size in an experimental mouse model of stroke.

J Cerebrovasc Endovasc Neurosurg · 2021 · PMC8743821 · PMID 34551509

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The CCL2 mRNA levels showed a trend to increase over time after stroke induction (day 1: 1.25±0.26 vs. 10.03±0.43, p=0.001; day 3: 4.85±0.07 vs. 10.33±0.98, p=0.001; day 5: 18.25±0.17 vs. 3.99±0.53, p=0.001; day 7: 35.79±0.33 vs. 2.66±0.79, p=0.001) ( Fig. 3C ).

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