The effects of lisdexamfetamine dimesylate on eating behaviour and homeostatic, reward and cognitive processes in women with binge-eating symptoms: an experimental medicine study.

For liking ratings, the interaction between drug condition, food type, and time approached significance ( F (1, 21) = 4.24, p = 0.05, η p 2 = 0.17) such that pasta was rated as less liked at the end of the meal after LDX versus placebo ( t (21) = −2.57, p = 0.018) but not at the start of the meal (Fig. 2 ).

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Cognition SST The effect of LDX on stop-signal commission errors was marginally significant: LDX reduced commission errors ( t (20) = −1.97, p = 0.06, d = 0.43), but there was no effect on omission errors ( t (19) = 0.67, p = 0.51, d = 0.15), no-signal RT ( t (20) = 1.59, p = 0.13, d = 0.35), SSD ( t (20) = 1.20 p = 0.24, d = 0.26), nor SSRT ( t (19) = −0.15, p = 0.88, d = −0.03) (Table 1 ).

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