Common <i>ALDH3A1</i> Gene Variant Associated with Keratoconus Risk in the Polish Population.

J Clin Med · 2021 · PMC8745142 · PMID 35011749

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

The presence of at least one minor allele A of rs1042183 (dominant model) was significantly associated with a higher risk of KC (OR = 2.06, 95%CI = 1.42–2.98, p = 0.00013), while in the additive model, the association of rs1042183 A alleles did not reach statistical significance (OR = 1.25 per each A allele, 95%CI = 0.99–1.57, p = 0.066).

also in 111,027 other papers

borderline significantno p-value reported

In the dominant model, we also observed a borderline significant association between rs141568499 and maximum corneal curvature, which was slightly higher in carriers of the minor C allele than in AA homozygotes (54.1 ± 6.0D vs. 51.7 ± 6.0D, p = 0.071). 3.

also in 11,409 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.