Patients receiving 2.5 mg/d EDP-305 ( n = 53) showed decreased HDL-C, increased apoB concentrations and a strong trend towards increased LDL-C compared to placebo ( n = 24), while plasma triglyceride levels were not affected [ 141 ].
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Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles.
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