Barely Significant
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PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice.

Sci Rep · 2022 · PMC8748717 · PMID 35013582

1
hedged sentence
0.0500
closest p · 1.0× alpha
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boldest claim

The sentences

a clear trendP = 0.05actually significant
Notably, significant upregulation of the keratinocyte terminal differentiation marker filaggrin (FLG; + 308%; P < 0.001) and a clear trend towards an increase (+ 132%; P = 0.05) in transcript levels of the epidermal differentiation complex protein loricrin (LOR) was observed in skin from SGC707-treated mice (Fig. 4 C).

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