nominally significantp < 0.05
Using the cis-pQTL instrument definition, 75 of the 1,013 associations (7.4%) that were investigated using MR IVW were nominally significant ( p < 0.05), while considering an FDR of 10% or less, 12 associations were significant, five of which were replicated ( p < 0.05) in analyses using the cis-eQTL instrument definition.