A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.

Blood Adv · 2021 · PMC8759116 · PMID 34535016

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0640

boldest claim

The sentences

highly significantP = 4.15 × 10 −10actually significant

Predictive value of the dichotomous score in risk subgroups When applying the cutoff defined in our previous study, PS29MRCdic was highly significant in the prediction of treatment failure (OR, 4.81; 95% CI, 2.95-7.93; P = 4.15 × 10 −10 ).

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reached borderline significanceP = .064so close (0.05 < p ≤ 0.1)

It reached borderline significance in the intermediate subgroup (OR, 1.85; 95% CI, 1.06-4.01; P = .064).

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