Polyphosphate expression by cancer cell extracellular vesicles mediates binding of factor XII and contact activation.

Because of the small sample sizes (13/21 for VTE or death and 6/21 for VTE only), these analyses were unable to demonstrate a statistically significant increased risk for future events in patients with elevated cHK/HK ( P = .11 and 0.39, respectively), although a clear trend toward increased risk is seen with cHK values in the range from 0.075 to 0.105.

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