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Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation.

Arthritis Res Ther · 2022 · PMC8762926 · PMID 35039075

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showed a trendno p-value reported
Col II stained area in the AF showed a trend to increase in the most herniated tissues, in opposite to Col I, suggesting ECM turnover regarding the collagen composition of the AF.

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