Barely Significant
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Genomic surveillance of SARS-CoV-2 in the state of Delaware reveals tremendous genomic diversity.

PLoS One · 2022 · PMC8769358 · PMID 35045124

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a clear trendno p-value reported
A clear trend can be observed with the average number of coding variants per sample increasing over time with a significant increase occurring near the end of March 2021 as highly mutated strains such as B.1.526 and B.1.1.7 became dominant.

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