Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer.

In keeping with this, in our study, some tumours which initially had an increase in TILs following FEC did not maintain this through taxane treatment, with a subsequent fall in TILs seen at the time of resection, albeit this was only a trend, and did not reach statistical significance.

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