Biomarkers-in-Cardiology 8 RE-VISITED-Consistent Safety of Early Discharge with a Dual Marker Strategy Combining a Normal hs-cTnT with a Normal Copeptin in Low-to-Intermediate Risk Patients with Suspected Acute Coronary Syndrome-A Secondary Analysis of the Randomized Biomarkers-in-Cardiology 8 Trial.

The per-protocol analysis, i.e., adherence to the proposed discharge of low-risk patients, demonstrated a higher risk reduction for MACE favoring the Copeptin group with an HR of 0.47 that showed a trend for statistical significance suggesting higher benefits with protocol adherence and thus corroborating the usefulness of DMS with either cTn or hs-cTnT for risk stratification and guidance of safe early discharge.

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