Calcium Signaling Pathway Is Involved in the Shedding of ACE2 Catalytic Ectodomain: New Insights for Clinical and Therapeutic Applications of ACE2 for COVID-19.

Biomolecules · 2022 · PMC8774087 · PMID 35053224

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Additionally, the administration of AC within 48 hours of admission showed that therapeutic AC was associated with a 14% reduction in hazard of mortality compared with prophylactic AC, though this did not reach statistical significance ( p = 0.08).

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