When split up by age group, the results of the whole‐brain analyses showed no statistical difference between the different groups except for T1 in the GM, where a barely significant difference ( p = .047) between individuals of around 60 and 100 years of age (Figure 4 , Figure S2 ) was found.
However, we could see a clear trend of longer T2 times with increasing age for both WM and GM.
When whole‐brain auto‐segmented results were compared to the ROI‐based results, we found a highly significant difference for T1 and T2 in GM and for T2 in WM for the oldest age groups (Figure 5 ). 3.5 Volumetric analysis No statistical difference in terms of volume between age groups was found for the various segmented volumes except for myelin between 65–74 years of age and the 95–105 years of age groups ( p = .038) (Figure S1 ).