Barely Significant
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Critical Role of E1623 Residue in S3-S4 Loop of Nav1.1 Channel and Correlation Between Nature of Substitution and Functional Alteration.

Front Mol Neurosci · 2021 · PMC8785683 · PMID 35082603

Europe PMCDOI
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hedged sentence
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closest p · 1.0× alpha
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boldest claim

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did not reach statistical significanceP > 0.05actually significant
The peak current density of the epilepsy-associated mutant E1623A was significantly decreased ( P < 0.05; Figures 4B–D ), while the mutant E1623Q was slightly increased when compared with that of WT, but did not reach statistical significance ( P > 0.05).

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