extremely significantP < 0.05
To select the most discriminant pathways, we chose levels of impact and extremely significant difference (impact > 0.3 and P < 0.05, respectively).
To select the most discriminant pathways, we chose levels of impact and extremely significant difference (impact > 0.3 and P < 0.05, respectively).
Differences were considered significant when P < 0.05, as well as those approaching significance (0.05 < P <0.10).
In addition, in phenylalanine, tyrosine, and tryptophan biosynthesis, indole-3-carboxylate increased but 3-(4-hydroxyphenyl) lactate and kynurenine showed a decreasing trend in the ROP group.