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Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability.

Antibodies (Basel) · 2022 · PMC8788544 · PMID 35076451

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a clear trendno p-value reported
Although each approach was successful in generating EGFR binders with increased humanness, there was a clear trend in stability and affinity retention across the humanization strategies.

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