Levothyroxine use and the risk of colorectal cancer: a large population-based case-control study.

Endocr Connect · 2022 · PMC8789018 · PMID 34860178

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did not reach statistical significanceno p-value reported

In line, we also found a modestly decreased risk of rectal cancer among levothyroxine users, although this did not reach statistical significance.

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borderline significantno p-value reported

Stratification by tumour subsite showed a borderline significant risk reduction of rectal cancer, while this was not seen for proximal colon cancer or distal colon cancer.

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