Barely Significant
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Reduced pituitary size in subjects with mutations in the THRB gene and thyroid hormone resistance.

Endocr Connect · 2022 · PMC8789019 · PMID 34860176

Europe PMCDOI
1
hedged sentence
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

a significant trendP = 0.09so close (0.05 < p ≤ 0.1)
The two subjects with increased TSH did not show significantly increased or decreased pituitary sizes in comparison to normal TSH levels (662 and 509 mm 3 , respectively). The analysis of volume and age revealed no significant correlation for the RTHß group (rho = −0.22, P = 0.37), whereas the healthy control group seems to have a faster decline of pituitary size across age and can be interpreted as a significant trend (rho = −0.44, P = 0.09) (see Fig. 2C ).

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