Barely Significant
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The association of Schistosoma and geohelminth infections with β-cell function and insulin resistance among HIV-infected and HIV-uninfected adults: A cross-sectional study in Tanzania.

PLoS One · 2022 · PMC8789133 · PMID 35077485

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

only marginally significantP = 0.06so close (0.05 < p ≤ 0.1)
However, among HIV-uninfected participants, geohelminth infection was associated with lower fat mass and waist circumference ( P <0.005, all) and with HbA1c, although this was only marginally significant ( P = 0.06) ( Table 5 ) Discussion In this study, we had hypothesized that helminth infection in HIV-uninfected participants would be associated with better insulin sensitivity and β-cell function whereas helminth-HIV co-infection would increase the risk of insulin resistance and β-cell function as result of severe immune activation and chronic inflammation [ 39 , 40 ].

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